WBRT EGFR TKI

WBRT for NSCLC brain metastases what is new?

Having you brain exposed for ionising gamma rays are not a good thing in general. Many recent studies questions the benefit of WBRT (Whole Brain Radiation "Therapy").

This is also true for NSCLC with EGFR and even recently (September 2017) there are studies on SCLC that starts to question the prophylactic use of WBRT.

Targeted therapies might be able to reach the brain, perhaps in a pulsed fashion, where you take a higher dose of the EGFR TKI once every 4 days.

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